The deadly duo of nanotubes and antibodies that search and distroy breast cancer cells

A recent development in nano medicine opened a possible gateway in curing aggressive form of breast cancer that is killing millions around the world, the positive development in this filed came from the National Institute of Standards and Technology (NIST) and its partners.

Nanotubes made of carbon cylinders about a nanometre in diameter which are single walled have been highly touted for potential applications such as ultra strong fibers, electrical wires in molecular devices, or hydrogen storage components for fuel cells which can also be used in the detection and destruction breast cancer cells.

HER2 is one of a family of genes that help regulate the growth and proliferation of human cells. Normal cells have two copies of HER2, but about 20 to 25 percent of breast cancer cells have multiple copies of the gene, resulting in the overproduction of a HER2-encoded protein. These multiple copies of HER2 tumors can successfully tracked and destroy by adding chicken immunoglobulin IgY antibody to nanotubes.

The two unique optical properties of carbon nanotubes allow this link to be exploited for improved detection and destruction of HER2 breast cancer cells. Near-infrared laser light at a wavelength of 785 nanometers reflects intensely off the nanotubes, and this strong signal is easily detected by a technique called Raman spectroscopy. Increase the laser light’s wavelength to 808, nanometers and it will be absorbed by the nanotubes, incinerating them and HER2 tumor cells to which they are attached and the wide genetic differences between human and avian species means that the chicken IgY antibody to HER2 reacts strongly with the target protein expressed on tumor cells while ignoring normal cells with other human proteins. The carbon nanotubes attached to the antibodies also become linked to the HER2 tumors.

Although this finding is in its infancy, scientist can see the future potential of this new technology. The next step for the research team is to see it working works with animals starting with mouse trails.

  • Share/Bookmark

Nanoparticle that can seek and destroy brain cancer cells

Scientists in Illionis are developing the fist ever  nanoparticle that can seek and destroy brain cancer cells without causing any damage to nearby cells.

The Studies shows that Titanium dioxide nanoparticles, witch are light sensitive particles which are used in sunscreens can destroy cancer cells when it is exposed to ultraviolet light. Even if it is effective in destroying caner cells scientists had difficulties in getting nanoparticles, each about 1 by 50,000th the width of a human hair, to target and enter cancer cells while avoiding healthy cells.

The  solution involves chemically linked titanium dioxide nanoparticles to an antibody that recognizes and attaches to GMB cells. The nanoparticles killed up to 80 percent of the brain cancer cells after 5 minutes of exposure to focused white light.The positive result of these experiments are a good hope for brain cancer treatment.

  • Share/Bookmark

What is Six pack abdomen – all the information about 6, 7 and 8 pack belly.

Six pack abs is something that all workout enthusiastic want to achieve especially men.  I need to explain the human abdominal muscle structure before explaining what exactly is six pack abs.

The Human abdominal muscles

abs-muscles

  • External abdomial Oblique

This is external oblique muscle and is the outermost muscle which covers the side of the abdomen. This muscle originates from the lower eight ribs, and then curves down and forward towards its insertion on the outer anterior crest of the ilium and (via the sheath of the rectus abdominis muscle) the midline linea alba and is broad, flat, and irregularly quadrilateral in shape.

  • Internal abdomial Oblique

This muscle is also known as internal oblique muscle and it is triangular in shape and compared to external oblique muscles this muscles is thinner and smaller. This muscle originates from Poupart’s ligament/inguinal ligament and the inner anterior crest of the ilium. The lower two thirds of it insert, in common with fibers of the external oblique and the underlying transversus abdominis, into the linea alba. The upper third inserts into the lower six ribs.

  • The transversus abdominis Muscle

The transversus abdominis muscle is flat and triangular, with its fibers running horizontally. It lies between the internal oblique and the underlying transversalis fascia. This muscle originates from Poupart’s ligament, the inner lip of the ilium, the lumbar fascia and the inner surface of the cartilages of the six lower ribs. It inserts into the linea alba behind the rectus abdominis.

  • The rectus abdominis muscles

These muscles are long and flat. The muscle is crossed by three tendinous intersections called the linae transversae. The rectus abdominis is enclosed in a thick sheath formed, as described above, by fibers from each of the three muscles of the lateral abdominal wall. They originate at the pubic bone, run up the abdomen on either side of the linea alba, and insert into the cartilages of the fifth, sixth, and seventh ribs.

  • The pyramidalis muscle

This abdominal muscle is small and triangular. It is located in the lower abdomen in front of the rectus abdominis. It originates at the pubic bone and is inserted into the linea alba half way up to the umbilicus.

How can you make your packs visible

The packs are the rectus abdominal muscles if we look at the muscle structure you can see eight packs ( four on each side ). In most of the people packs go under belly fat and make it invisible, losing those unwanted fats and toning all your abdominal muscles will make the packs clear and visible.

There are lot of fat burning methods, which include resistance trainings like stomach crunches, leg lifts and some aerobic workouts can drastically reduce body fat especially the fat around your abs, also there are lot of stomach trimming machines available in the market, you have to choose the better one for you .

Facts about seven packed and eight packed abs

Eight packs are formed when the rectus abdominal muscles near the lower abdominal area gets visible, 8 packs wont be visible even for a zero fat guy, because the partition between the 7 th and 8 th packs wont be that visible due the presence of elastic intestine beneath the muscles which pushes the muscles outward from the middle resulting in the less visible central partition. so the 8 ful packs wont be visible , in that case we can call it 7 packed abs ,  when the partition of the bottom packs gets invisible. But in some rare cases and rare occasions like when a guy starves, the full 8 packs gets visible

  • Share/Bookmark

Nanodiamond surface with PEI800 for biocompatibile gene therapy

Studies conducted by Northwestern researchers are showing us that Nanodiomonds can be used as a vehicle for gene delivery they do it by by functionalizing the nanodiamond surface with PEI800 and it is going to revolutionize the genetic medicine front, this new technology combines key properties in one approach, ie : enhanced delivery efficient along with outstanding bio compatibility.This technology used surface-modified nanodiamond particles that can successfully deliver DNA into mammalian cells this is 70 times greater than that of a conventional gene delivery standard which are very toxic to the cells.
Doses of nanodiamond-PEI800 that were three times higher than that of the high-molecular weight PEI revealed a highly bio-compatible complex. Nanodiomaonds can also be used effectively in delivering therapeutic proteins
Gene therapy with the aid of nanodiamonds holds promise in treating a variety of diseases including cancer, and diabetes,heart disease and many other diseased, It can also aid the new anti aging gene therapy.

Source of information http://www.eurekalert.org/pub_releases/2009-09/nu-pon090109.php

  • Share/Bookmark

Nano bio technology for terminating brain tumor

Thousands of people die from malignant brain tumors every year, and the tumors are resistant to conventional therapies. This nano-bio technology may eventually provide an alternative form of therapy that targets only cancer cells and does not affect normal living tissue.

This new therapy depend on a two pronged approach. Titanium dioxide is a versatile photoreactive nanomaterial that can be bonded with biomolecules. Nanoparticles recognise and bind specifically to cancer cells when it is linked to an antibody. Focused visible light is shined onto the affected region, and the localized titanium dioxide reacts to the light by creating free oxygen radicals that interact with the mitochondria in the cancer cells. Mitochondria act as cellular energy plants, and when free radicals interfere with their biochemical pathways, mitochondria receive a signal to start cell death.

With this method it is possible to effectively attack the cancer which invade surrounding healthy cells using titanium dioxide unlike other cancer treatments like  radiotherapy and chemotherapy. But so far the tests have been done only on cells in a laboratory setting, animal testing is yet to be done and is planned for the next phase. Results show an almost 100 percent cancer cell toxicity rate after six hours of illumination, and 80 percent after 48 hours  and also other types of  cancers can be cured as well using different targeting molecules, but research is in the early stages.

Reffed form http://pubs.acs.org/doi/abs/10.1021/nl901610f

  • Share/Bookmark

Body builders diet – Food that helps to build muscles

Building our body muscles and gaining weight needs dedication and effort. With the gaining of muscles mass one become strong. Any one can gain muscle mass with regular resistance workouts and protein rich diet. I am going to write down about some protein rich diets which helps in muscle building

  • Natural supplements for body builders.

Egg white
Egg whites contains good amount of proteins, egg whites contain no fat and although the egg yolk is high in cholesterol, consuming egg whites by avoiding yolks helps to build muscle mass, body builders use to eat ten to twenty egg whites per day.  Egg whites provide us with essential amino acids that speed up the pace of muscle recovery. Essential amino acids are proteins that are necessary for good health yet are not naturally produced by the body and are therefore only accessible through diet rich in  liquid egg whites which are safe to consume raw, boiled or add them into shakes by body builders.

Protein rich Soy beans.
Soy bean diet is naturally rich in protein, which helps to build muscles. Soy beans are considered by some to be a complete protein source in that they provide all the essential amino acids for human nutrition. Recent studies conducted by American College of Sports Medicine (ACSM) proved us that post-workout consumption of isonitrogenous and isoenergetic soy drink to be statistically significant in hastening mass, fat-bone free mass (FBFM) and increases in strength, when compared to other post-workout formulations. Another report suggest that soy supplementation might hold for the bodybuilding population, as a legitimate alternative to the whey protein.

Skinless Chicken
Skinless chicken is a good source of protein and it is one of the favorite diet of body builders.

Fish for building muscles
Fishes are a very good source of protein, fishes like Tuna got very high amount of protein a can of tuna can easily supply you with 30 grams of protein. Tuna can be consumed as sandwiches, salads and other dishes.

Why I wont recommend Milk protein and Red meat protein
Milk protein and Beef are widely recommended as body building supplements, but consuming it can give rise to other health complication, you can consuming the safe supplements I mentioned above in a good quantity if you want to build muscles.

Muscle building needs a strict resistance workout regime ,  you need to increase the resistance step by step and also you should supply the body with protein supplements for building muscles.

  • Share/Bookmark

Nanosheets for scar free surgical stitches

Researchers at Tokyo’s Waseda University have used the biodegradable material to develop nanosheets for suture treatment which can replace Poly-L-lactide has been used previously as degradable stitches and in
drug delivery

Wounds made in mice stomatches healed without scarring the tissue when the researchteam applied sheets to incisions. Findings were published in the journal Advanced Materials. Shinji Takeoka, professor in the Department of Life Science and Medical Bioscience at Waseda University said, “This new approach would constitute a perfect candidate for an alternative to conventional suture/ligation procedures, from the perspective not only of a minimally invasivesurgical technique but it can also reduce the operation times,” The nanosheets which is only about 20 nanometers in thickness could be used for general wound dressing, but will also be very useful in endoscopic surgery, plasticsurgery  and regenerative medicine. Clinical trials could still be several years away.

Courtesy : http://www.plasticsurgerypractice.com/eReport/2009-08-17_05.asp

  • Share/Bookmark

Chicken health benefits – healthy ways of eating chicken

Chicken is one of the safest meat available and it is the most widely consumed meat on the planet, Chicken in packed with vitamins and nutrients that are essential for positive health. but we need to take some care before eating chicken.

Unhealthy parts of a chicken
Chicken is white meat which tastes good and almost every one like the taste of chicken, but we need to remove the unhealthy eatable parts of chicken before preparing it, Chicken skin contains majority of ( 3/4) chicken fat, its advised to completely remove the chicken skin before preparing, chicken meat with out skin is low calorie, low carb food packed with protein, even if chicken liver is packed with lot of essential vitamins it is high in cholesterol and it is one of the  stuffs that contains very high amount of  LDL ( bad cholesterol ) for those who care for their cholesterol levels should throw chicken liver into the deepest corner of their trash bin.

Good to avoid chicken fed with  growth drugs
It will be good to buy chicken from a branded and trusted farmers, those who avoid using Antibiotics, Arsenic and Growth hormones on faster growth of chicken now a days these drugs are illegal to use in poultry.

Skinned chicken meat nutritional information
Chicken meat is power packed with proteins it makes one of the favorite food for body builders due to its muscle building potential. skinned chicken meat is very low in fat if we compare it with other meats. Chicken is a good source of niacin, B-6, B-12, vitamin D, iron and zinc which is essential to maintain a healthy body.  Consuming chicken helps to slow down aging, trance mineral selenium found in chicken is an anti aging component. Selenium is of fundamental importance to human health. It is an essential component of several major metabolic pathways, including thyroid hormone metabolism, antioxidant defense systems and immune function. Evidence from prospective studies, intervention trials and studies on animal models of cancer have suggested a strong inverse correlation between selenium intake and cancer incidence.

Health benefits of Chicken feet and leg
Scientific studies are giving us more and more proofs about the health benefits of chicken feet and leg which are often regarded as chicken waste in most of the places, but they are used to make soups in orient, extracted collagen from chicken legs and tested for its ability to act as an ACE inhibitor in the laboratory studies, which have the ablility to reduce blood pressure in people with high blood pressure.

  • Share/Bookmark

Weight loss food for Obese and those who want to cut down their weight

Having those excess fat on our bodies make you slow less attractive and will make us more vulnerable to diseases, Physical workouts are very important to burn those unwanted fat from our body and it is also very important to follow strict diet that helps fat burning.

Green tea magic.

Scientific studies have shown us  that regular green tea drinkers can burn fat in their body by a process called thermogenesis – the process of heat production in organisms, caffeine and flavonoids found in green tea is the reason for the termogenesis effect. It is advised by most dietitians for those who really want to cut their weight down.

Grapes and weight loss

soybeans

soy beans

Drinking a glass of grape juice every morning can actually help you to cut down your weight.Flavonoid content in grapefruit  performs double-duty as a fat-burning molecule which helps balance out blood sugar levels and helps prevent metabolic syndrome.

Soy beans and Weight loss

Researchers have found out that regular consumption of diet rich in  Soy protein can increase metabolisms which will result in weight loss.

Chili peppers fat burning power

Studies shows that Chilli Peper can help in burning fat due to the precence of  heat producing molecule capsaicin. Its good to add peper powder in your dishes if you are serious about burning fat.  Eating chili peppers suppresses hunger and prolongs the feeling of fullness, reducing appetite that way it helps people who are on a diet. Pepper can also add a nice flavor to your dishes.

Turmerics slimming power

Turmeric can fight acuumlalation of body fat due to the presence of a naturally occurring phytochemical called curcumin. Angiogenesis activity  allows new blood vessels to form in the body, which in turn permits the growth of  fat tissue and consuming turmeric through our daily diet can reduces overall blood vessel growth and overall fat tissue growth due the presence of the antioxidant curcumin.

  • Share/Bookmark

Workouts for woman and its benifits

Physical Workouts are very important for us to stay fit and active, men and woman need to follow different workout methods. Woman should do workout that compliment their body shape.Woman should concentrate more on aerobics and muscle toning workouts rather than muscle building workouts if they want to maintain their feminine physique. but there are some females who go for muscle building workouts, but if you ask me I will rate them as masculine but there may be people who admire them. Regular workouts helps woman to improves mobility and strength in later life, workouts helps woman to live longer and improves quality of life, helps to prevent bone mass loss, read my articles under A Great body facts and physical exercise programs to more about the benefits.woman_workouts

Workout Advices for woman

To look sexy and healthy woman should go for tummy trimming workouts like stomach crunches, leg lifts etc A flat stomach looks good for both men and woman and helps them look good in almost all clothes. Sit ups can give good definition to their feminine hip curves and helps to tone leg and hip muscles. Aerobics workouts are good for both sexes. Woman looks good with petite shoulders, but toning the shoulder muscles are important for woman to stay healthy,  light push ups and light weight dumbbell curls will help them to tone their shoulder muscles.

Feminine Health benefit
Studies have shown us that women who remains physical active after menopause can reduce the risk of breast cancer.

Health benefits for pregnant woman
Studies have shown that mild to moderate workouts in  pregnant woman can strengthen and improve overall physiologic and musculo-skeletal health as well as pregnancy related symptoms. Exercise such as aerobics, impact and non impact activities, resistance training and swimming can ease down musculo-skeletal pain, lowers maternal Blood pressure, improves post-partum mood which includes sadness, and reduces swelling.

  • Share/Bookmark