HealthAndAdvices » Nanotechnologie en caner

Nanodiamond surface with PEI800 for biocompatibile gene therapy

admin — Fri, 04 Sep 2009 18:30:45 +0000

Studies conducted by Northwestern researchers are showing us that Nanodiomonds can be used as a vehicle for gene delivery they do it by by functionalizing the nanodiamond surface with PEI800 and it is going to revolutionize the genetic medicine front, this new technology combines key properties in one approach, ie : enhanced delivery efficient along with outstanding bio compatibility.This technology used surface-modified nanodiamond particles that can successfully deliver DNA into mammalian cells this is 70 times greater than that of a conventional gene delivery standard which are very toxic to the cells.
Doses of nanodiamond-PEI800 that were three times higher than that of the high-molecular weight PEI revealed a highly bio-compatible complex. Nanodiomaonds can also be used effectively in delivering therapeutic proteins
Gene therapy with the aid of nanodiamonds holds promise in treating a variety of diseases including cancer, and diabetes,heart disease and many other diseased, It can also aid the new anti aging gene therapy.

Source of information http://www.eurekalert.org/pub_releases/2009-09/nu-pon090109.php

Nano bio technology for terminating brain tumor

admin — Mon, 24 Aug 2009 09:33:46 +0000

Thousands of people die from malignant brain tumors every year, and the tumors are resistant to conventional therapies. This nano-bio technology may eventually provide an alternative form of therapy that targets only cancer cells and does not affect normal living tissue.

This new therapy depend on a two pronged approach. Titanium dioxide is a versatile photoreactive nanomaterial that can be bonded with biomolecules. Nanoparticles recognise and bind specifically to cancer cells when it is linked to an antibody. Focused visible light is shined onto the affected region, and the localized titanium dioxide reacts to the light by creating free oxygen radicals that interact with the mitochondria in the cancer cells. Mitochondria act as cellular energy plants, and when free radicals interfere with their biochemical pathways, mitochondria receive a signal to start cell death.

With this method it is possible to effectively attack the cancer which invade surrounding healthy cells using titanium dioxide unlike other cancer treatments like radiotherapy and chemotherapy. But so far the tests have been done only on cells in a laboratory setting, animal testing is yet to be done and is planned for the next phase. Results show an almost 100 percent cancer cell toxicity rate after six hours of illumination, and 80 percent after 48 hours and also other types of cancers can be cured as well using different targeting molecules, but research is in the early stages.

Reffed form http://pubs.acs.org/doi/abs/10.1021/nl901610f

Nanotechnology and overian caner

admin — Fri, 31 Jul 2009 15:24:34 +0000

Use of nanotechnology is killing ovarian cancer cells

Gene therapy with the aid of nanotechnology can cure ovarian cancer, experiment conducted by US Researchers was able to deliver tiny synthetic particles carrying a payload of toxin worked as well as chemotherapy at killing ovarian cancer in mice without side effects. The highlights of the study is the potential of nanotechnology in the design and manipulation of tiny synthetic particles, as a non viral way of getting DNA into cells, in the past there were interesting success with viruses but there are some safety concerns with Viruses. When they injected the treatment into the abdominal cavity of animals with ovarian cancer, it worked as well or better than the traditional chemotherapy drug combination of cisplatin and paclitaxel, which can cause DNA damage and a variety of side effects.

The Scientists tested different compounds until they found a biodegradable polymer that made a suitable delivery vehicle.To form the nanoparticle, the polymers are mixed with a gene that produces a modified form of the diphtheria toxin which is harmful only to ovarian cancer cells.

Use of nanotechnology for delivering drugs to cure ovarian cancer in humans is still have to be tested, researchers are planning to conduct test in humans within a year. if this test work it will be a promise for a new treatment for ovarian cancer, which kills thousands of woman all around the world.

Bio nanobots that kills cancer cells

admin — Thu, 02 Jul 2009 21:32:44 +0000

One more feather on the cap of nanotechnology in curing cancer, with the help of a new method called trojan horse therapy. Australian Scientists Dr Jennifer MacDiarmid and Dr Himanshu Brahmbhatt, who formed EnGenelC Pty Ltd in 2001 discovered a very effective method which they call Trojan horse” therapy to combat cancer using bacterially derived nano cell that helps to penetrate and disarm the cancerous cells, after that a second nanocell is send to cancerous cells which kills it chemotherapy drugs.

The “trojan horse” therapy has the potential to directly target cancer cells with chemotherapy, rather than the current treatment that sees chemotherapy drugs injected into a cancer patient and attacking both cancer and healthy cells.

Cancer fighting nano sensors

admin — Mon, 15 Dec 2008 21:18:39 +0000

Efforts of US scientists payed the way for the discovery of nano sensors that can detect traces of cancer causing chemical insdie human cells.
Scientists can easily detect particular chemical from the variation of the light signals emitted by the sensor when it interacts with DNA inside a living cell, It can also be used for measuring the effectiveness of cancer fighting dugs inside a human body. These sensors are coated in DNA so can be easily injected into human body without causing any harm.
These sensors will be a stepping stone for future discoveries of nano medicines , what I feel is that nanotechnology is gonna change the world we live.